Margin of exposure deutsch
WebJan 1, 2010 · The MOE is defined as the ratio of the no-observed-adverse-effect level (NOAEL) or benchmark dose lower confidence limit (BMDL) for the critical effect to the theoretical, predicted, or estimated exposure dose or concentration (WHO, 2009).For carcinogenic processes mediated via a DNA-reactive mode of action (MOA) (Preston and … WebTwelve genotoxic and carcinogenic chemicals that can be present in food were selected for calculation of a Margin of Exposure (MOE) between a point of departure on the dose-response for oral carcinogenicity in animal studies and estimates of human dietary exposure. The MOE can be used to support prioritisation of risk management action and, …
Margin of exposure deutsch
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Webenables the estimation and assessment of exposure to substances from consumer products that are used indoor and their uptake by humans. CSA Chemical safety assessment CSR … WebMar 30, 2012 · The Scientific Committee reiterates its view expressed in 2005 that in general a margin of exposure of 10,000 or higher, if it is based on the BMDL10 from an animal study, and taking into account overall uncertainties in the interpretation, would be of low concern from a public health point of view; the magnitude of an MOE however only ...
WebMany translated example sentences containing "exposure" – German-English dictionary and search engine for German translations. Look up in Linguee; Suggest as a translation of "exposure" ... selectively chosen based on their solid financial solvency margin (for more information on the Group's retrocession policy, refer to Paragraph 9.2.1.1 (c WebDer Margin of Exposure ergibt sich als Verhältnis aus der menschlichen Exposition ( Umfang des Kontakts mit einem Stoff ) und der im Tierversuch festgestellten oder berechneten Effektdosis für eine gegebene Tumorinzidenz ( i.d.R. BMDL10 = Benchmarkdosis; tumorauslösend bei 10 % der Tiere im Tierexperiment ). www.bfr.bund.de
WebDer Margin of Exposure ergibt sich als Verhältnis aus der menschlichen Exposition ( Umfang des Kontakts mit einem Stoff ) und der im Tierversuch festgestellten oder berechneten … WebColors vary linearly with powers of 10 of aromatase inhibition resulting from W and margin of exposure combinations, from red ([10.sup.-2]) to blue ([10.sup.-80]). High-throughput …
WebMargins of exposure (MOEs) and risk quotients (RQs) are measurements of potential risk used in the risk assessment of substances. Both MOEs and RQs are ratios of a …
WebIn toxicology, the margin of exposure (or MOE) of a substance is the ratio of its no-observed-adverse-effect level to its theoretical, predicted, or estimated dose or concentration of … ship hamburgerWebMargin of Exposure (MOE), Margin of Safety (MOS): From: Glossary for Chemists of Terms Used in Toxicology. In IUPAC Standards Online . Berlin, Boston: De Gruyter. ship hampshire 1748WebStandard margin-of-exposure (MOE) calculations using the geometric mean of the data are performed however, probability (Student s f-test) and distributional (Monte Carlo … ship hamilton sleighWebMargin of exposure, genotoxic, carcinogenic, impurities, additives, flavourings 1 Impurities considered include for example unavoidable contaminants, residuals and by-products resulting from a production process 2 On request from EFSA, Question No EFSA-Q-2012-00233, adopted on 8 February 2012. ship hamsterWebMargin of exposure (English to German translation). Translate Margin of exposure to English online and download now our free translation software to use at any time. ship hamilton countyWebDer Margin of Exposure ergibt sich als Verhältnis aus der menschlichen Exposition ( Umfang des Kontakts mit einem Stoff ) und der im Tierversuch festgestellten oder berechneten … ship handlesWebDer Margin of Exposure ( MOE) ist ein von Risikobewertern verwendetes Instrument zur Abwägung möglicher Sicherheitsbedenken in Bezug auf in Lebens- und Futtermitteln … ship hammer