WebSide effects in men resulting from the antiandrogenic and antigonadotropic properties of CPA include physical demasculinization, sexual dysfunction (including loss of libido and erectile dysfunction ), absence of ejaculate, impaired spermatogenesis, testicular atrophy, and reversible infertility. WebCyproterone acetate suppresses the secretion of ACTH and the plasma concentration of cortisol. Fatigue and weakness are common side effects, probably as a consequence of secondary adrenal insufficiency. This agent lacks gluconeogenic activity and does not appear to produce cushingoid features.
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WebMar 4, 2024 · weight changes (increase or decrease) decreased sexual drive; headache; depressed mood; nausea and other gastrointestinal complaints; breast pain, changes in … WebCyprostat also reduces the number of sperm and the amount of ejaculate you produce. Weight gain You may put on weight, or your ankles and legs may become swollen. This … how many ft is 50 miles
Cyproterone (Oral Route, Intramuscular Route) - Mayo Clinic
WebAbstract. Objective: The aim of this study was to investigate the effect of oral contraceptive Diane 35 (ethinylestradiol + cyproteroneacetate EE/CPA) which is widely used in the … Weight gain can occur with CPA when it is used at high doses. Some of the side effects of CPA can be improved or fully prevented if it is combined with an estrogen to prevent estrogen deficiency. Few quantitative data are available on many of the potential side effects of CPA. See more The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized. It is generally well-tolerated and has a mild side … See more Side effects in men resulting from the antiandrogenic and antigonadotropic properties of CPA include physical demasculinization, sexual dysfunction (including loss of libido and erectile dysfunction), absence of ejaculate, impaired See more Liver toxicity The most serious potential side effect of CPA is hepatotoxicity. A variety of manifestations of See more Belisle and Love (1986) directly compared Diane (ethinylestradiol 50 μg/day and CPA 2 mg/day) alone versus the combination of Diane and CPA 100 mg/day (Androcur) in 158 women with … See more High prolactin levels CPA increases prolactin levels and can produce hyperprolactinemia (high prolactin levels) due to its progestogenic activity and consequent … See more Lipid changes High doses of CPA have been found to decrease levels of HDL ("good") cholesterol. Unfavorable blood lipid profile changes are a … See more Adrenal insufficiency Abrupt withdrawal of CPA can be harmful, and the package insert from Schering AG recommends the daily dose be reduced by no more than 50 mg at intervals of several weeks. The concern is the manner in which CPA affects the See more WebYou can lose weight by exercising regularly and eating a healthy, balanced diet. Your diet should include plenty of fruit and vegetables, (at least 5 portions a day), whole foods … how many ft is 92 inch